Verwandte Artikel zu Chromatin and Disease: 41 (Subcellular Biochemistry)
Inhaltsangabe
This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme.
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Reseña del editor
This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme.
Reseña del editor
The packaging of genomic DNA together with core histones, linker histones, and other functional proteins into chromatin play key roles in nuclear processes such as transcription, replication, repair and recombination. Research in the last two decades has unveiled the fact that many diseases involve an aberration of these processes at the chromatin level. Similarly, it is becoming clear that different processes such as chromatin assembly, remodeling of chromatin structure coupled to covalent modification of histone and non-histone proteins, chromatin modifying enzymes and last but not the least, important DNA-templated phenomena are the potential drug targets for diseases such as different types of cancer, neurodegenrative diseases, AIDS etc. While, the earliest form of chemotherapy employed chromosomal DNA cleavage and modification, the study of epigenetic functions and therapy has recently emerged as a frontline research activity. At this juncture we felt the necessity to make an overview of the current research activities in the above areas. It is obvious that this collection starts with our current knowledge of chromatin structure. This work is the first endeavor to present different aspects encompassing the above theme.
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Chromatin and Disease (Subcellular Biochemistry, 41, Band 41) Hrsg. Tapas K. Kundu ; Hrsg. Dipak Dasgupta
Anbieter: Book Broker, Berlin, Deutschland
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Zustand: Sehr gut. 2007. 472 S. Alle Bücher & Medienartikel von Book Broker sind stets in gutem & sehr gutem gebrauchsfähigen Zustand. Dieser Artikel weist folgende Merkmale auf: Altersentsprechend nachgedunkelte/saubere Seiten in fester Bindung. 1. Auflage. Leichte Gebrauchsspuren. Sprache: Englisch Gewicht in Gramm: 1001 Gebundene Ausgabe, Maße: 15.75 cm x 2.29 cm x 23.62 cm. Artikel-Nr. 661036105
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Chromatin and Disease.
Verlag:
Dordrecht, Springer Netherland., 2007
ISBN 10: 1402054653
ISBN 13: 9781402054655
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Anbieter: Universitätsbuchhandlung Herta Hold GmbH, Berlin, Deutschland
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2007. 16 x 24 cm. XIV, 458 S. XIV, 458 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. (Subcellular Biochemistry). Sprache: Englisch. Artikel-Nr. 512ZB
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Chromatin and Disease
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Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher. Artikel-Nr. 3291902/12
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Chromatin And Disease
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Chromatin and Disease
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Zustand: New. pp. 472. Artikel-Nr. 7551984
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Chromatin and Disease
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Zustand: Used. pp. 472. Artikel-Nr. 18295973
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Chromatin and Disease (Subcellular Biochemistry, 41)
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Chromatin and Disease
Verlag:
Springer Netherlands, Springer Netherlands Mär 2007, 2007
ISBN 10: 1402054653
ISBN 13: 9781402054655
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Buch. Zustand: Neu. Neuware -It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics. In the light of these advances, it happens to be the right time to explore current insights into various aspect of chromatin and disease connection under one cover. Authors who are actively involved in chromatin research and have made several original contributions to develop latest paradigms in the field have written the chapters of this book. Significantly, the authors¿ repertoire is truly international. They come from eight different countries of Asia, Europe and America. The book has been divided into three different parts. Part I introduces the reader to the dynamic nature of chromatin structure and its link to diseases. First two chapters in this part deal with the chromatin architecture, chromatin dynamics in the cell cycle and molecular mechanism of chromatin remodeling.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 472 pp. Englisch. Artikel-Nr. 9781402054655
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Chromatin and Disease
Verlag:
Springer Netherlands, Springer Netherlands, 2007
ISBN 10: 1402054653
ISBN 13: 9781402054655
Neu
Hardcover
Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics. In the light of these advances, it happens to be the right time to explore current insights into various aspect of chromatin and disease connection under one cover. Authors who are actively involved in chromatin research and have made several original contributions to develop latest paradigms in the field have written the chapters of this book. Significantly, the authors' repertoire is truly international. They come from eight different countries of Asia, Europe and America. The book has been divided into three different parts. Part I introduces the reader to the dynamic nature of chromatin structure and its link to diseases. First two chapters in this part deal with the chromatin architecture, chromatin dynamics in the cell cycle and molecular mechanism of chromatin remodeling. Artikel-Nr. 9781402054655
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Chromatin and Disease (Subcellular Biochemistry)
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