Excerpt from Radium, Vol. 7: A Monthly Journal Devoted to the Chemistry, Physics and Therapeutics of Radium and Radio-Active Substances; April, 1916
It usually seems, although conditions are so diverse that it is difficult to judge, that if a dose be doubled less than half the previous exposure will be needed to produce the same effect.
Speaking generally, tubes Of 25 mcs. Contained in screens Of silver 1 mm. Thick, or platinum mm. Thick, placed in a growth 2 - 3 cm. Apart for twenty-four hours has been the most usual treatment given at the department, but it is Obvious that every additional tube buried in a tumour must increase the total radiation traversing any given point in the mass, so that the aggregate dosage must always be considered. If we could find out exactly the amount Of radiation therapeutically needed per cc. Of a tumour, and an accurate method of estimating the size Of cancer growths, there would merely be left to the physicist a mathematical calculation Of the quantities to be used to produce total absorption, and the use Of a sufficient number Of tubes would remove the possibility Of local over dose.
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