Ptomaïnes, Leucomaïnes, and Bacterial Proteids: Or the Chemical Factors in the Causation of Disease (Classic Reprint) - Softcover

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Excerpt from Ptomaïnes, Leucomaïnes, and Bacterial Proteids: Or the Chemical Factors in the Causation of Disease

IT is customai y to divide bacteria into the parasitic and the saprophytic. The obligate parasite can live only on living mattei; the obligate saprophyte can live Only on dead matter. Since allb attempts to grow the bacilli Of syphilis and leprosy on artificial media have failed, they are probably obligate parasites. True parasitic germs do not prove Speedily fatal to their hosts, because their continued existence depends upon the continued existence of their host, or on their transference to another host. Leaving out of consideration the obligate bacterial parasites, about which very little Is known at best, the above classification becomes of but little Importance to us in a study of the causal rela tion of germs to disease, because a given bacteiium may grow and multiply in one part of the body, while it is unable to do so in another or it may thrive in one Species of animal, while it finds the conditions unfavorable in an other Species or similar differences may exist in individual members of the same species. Thus, the white rat is ordi narily and naturally immune against the bacillus of anthrax, but if the rat be exhausted by being kept on a Small tread mill for some hours it becomes susceptible to anthrax. Recognizing these facts, we propose that bacteria be divided into the toxicogenic and the non-toxicogenic. Since we know of no infectious disease in which poisons are not formed, the toxicogenic germs only are of interest to us.

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