Advances in Metallodrugs: Preparation and Applications in Medicinal Chemistry - Hardcover

Über die Autorin bzw. den Autor

Shahid-ul-Islam is a Principal Project Scientist at the Indian Institute of Technology Delhi, where he works on the chemistry of metal-based natural dyes using advanced technologies. He received his PhD in Chemistry from Jamia Millia Islamia (A Central University), New Delhi, India, in 2017. He has to his credit several research journal publications, patents and books with the Wiley-Scrivener imprint.

Athar Adil Hashmi studied chemistry at Aligarh Muslim University, India and obtained his PhD in 1994. From 1990 to 2007 he held positions at the department of chemistry, Jamia Millia Islamia (Central University), New Delhi, India. Since April 2017 he is working as a visiting Professor at King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. His work area includes organometallic chemistry, metal containing polymers and bio-inorganic chemistry. Along with his international publications, book chapters, he has guided 30 postgraduate projects and 13 PhD students.

Salman Ahmad Khan received his PhD in Organic Chemistry from the Jamia Millia Islamia (JMI) (A Central University), New Delhi, India, in 2007. Since 2009 he has been with the Department of Chemistry, King Abdulaziz University, Jeddah, Saudi Arabia, where he is an Associate Professor. His current research interests include Heterocyclic Chemistry, Chromones, Chalcones, Anthraquinones, Photophysical, Physicochemical, Multi steps reactions, one pot multi component synthesis and Nanotechnology. Dr. Salman is an active researcher and has published more than 100 research articles in various reputed international journals.

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The book provides a recent update and achievements in the preparation and application of newly designed metal-based drugs.

Over the past few decades, medicinal inorganic chemistry as an interdisciplinary sub-area of bioinorganic chemistry, has received a growing attention of researchers in the search for promising antimicrobial, antimalarial, antiviral, and antitumor chemotherapeutic agents. An excellent compilation of reports on metal complexes has revealed the potency of metal complexes as better therapeutic agents. Metal-containing drugs have several promising advantages over organic ligands and have gained the trust of researchers after the worldwide approval of the drug cisplatin. Their distinct mechanism of action makes them perfect candidates as alternatives to the conventional drugs to which resistance has already been shown. In this direction, a huge number of transition metal complexes have been synthesized and evaluated for their biological profiles.

This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlighting the application areas of newly discovered metallodrugs.

This important and topical book:

• Discusses newly adopted methods involved in the design of effective metallodrugs
• Provides up-to-date developments in the application of metal-complex drugs
• Discusses the role of metallodrugs as promising chemotherapeutic agents

Audience

The book will be used extensively by researchers, engineers, and postgraduate students working in the fields of medical science, pharmacy, biotechnology and biomedical engineering.