HIV Reservoirs: Methods and Protocols: 2407 (Methods in Molecular Biology) - Hardcover

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This book details the development of methods and models to study the HIV-1 viral reservoir with the ultimate goal of achieving a functional cure of HIV infection. Chapters are divided into six parts covering&nbsp;cell lines,&nbsp;<i>in vitro</i>&nbsp;and <i>ex vivo </i>primary cell models of persistent infection, <i>in vitro</i>&nbsp;and <i>ex vivo </i>tissue-derived models, infected animal models human immune cells, methods of detection and analysis of the reservoir, and current approaches to achieve either a functional cure or cART-free long-term remission.&nbsp;Written in the format of the highly successful&nbsp;<i>Methods in Molecular Biology&nbsp;</i>series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.<p>&nbsp;</p><p>Authoritative and cutting-edge,&nbsp;<i>HIV Reservoirs: Methods and Protocols</i>&nbsp;provides&nbsp;a comprehensive, updated collection of state-of-art methodologies and models to tackle the HIV-1 viral reservoir.</p>