The book provides a comprehensive examination of pancreatic cancer, integrating global insights with an African-focused perspective. Understanding Pancreatic Cancer: Global Strategies and African Perspectives is structured into five parts, each addressing key aspects of the disease, from epidemiology to future innovations in care. Part I (Chapters 1 and 2) explores the global and African contexts, highlighting disparities in prevalence, diagnosis, and healthcare infrastructure. Part II (Chapter 3) delves into the biological and molecular mechanisms of pancreatic cancer, including genetic mutations and emerging therapeutic targets. Part III (Chapters 4 and 5) focuses on precision medicine and early detection, discussing advances such as artificial intelligence (AI) and biomarker-driven approaches. Part IV (Chapters 6-8) covers treatment strategies, from conventional therapies to novel interventions like immunotherapy and targeted treatments. Finally, Part V (Chapters 9-11) emphasizes the importance of advocacy, research, and policy reforms, outlining strategies for improving patient outcomes and shaping the future of pancreatic cancer care.
By bridging scientific advancements with real-world challenges, this book serves as an essential resource for researchers, clinicians, and policymakers working to enhance pancreatic cancer diagnosis, treatment, and prevention—both in Africa and globally.
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Zodwa Dlamini is a Professor of Molecular Oncology and the founding Director and the Executive Head of the Pan African Cancer Research Institute (PACRI) in South Africa. She is the Director of South African Medical Research Council (SAMRC) Precision Oncology Research Unit (PORU). She is the DSTI/NRF SARChI Chair in Precision Oncology and Cancer Prevention (POCP). She is a member of the American Association for Cancer Research (AACR) Advisory Group on Sub-Saharan Africa. She is a member of the AACR Pathology Resources in Africa Advisory Group. Professor Dlamini is a member of the African Organisation for Research and Training in Cancer (AORTIC) Research Committee Scientific Advisory Board. She is an elected member of the Academy of Science of South Africa. Professor Dlamini is an overseas Fellow of the Royal Society of Medicine (London) and a member of the New York Academy of Sciences.
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