Switchable and Responsive Surfaces and Materials for Biomedical Applications (Woodhead Publishing Series in Biomaterials, Band 92) - Hardcover

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Semprus BioSciences, Cambridge, MA, USA

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Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics.

The first part provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors.

Switchable and Responsive Surfaces and Materials for Biomedical Applications will be a key resource for researchers and developers in industry and academia who are concerned with surface science of biomaterials. It should particularly appeal to biomaterials scientists who are focusing on biosensors, drug delivery and tissue engineering.

Dr Zheng Zhang is the Founding Scientist and the Principal Scientist of Semprus BioSciences (now a wholly owned subsidiary of Teleflex, Inc.). He is an inventor of several surfaces and polymers for various biomedical and engineering applications. He heads the research team that focus on developing the next generation implantable medical devices and biosensors.