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This book provides a snapshot of the current state-of-the-art of the understanding of the fundamentals of ICPMS, instrumental development, methods development, spectral interpretation and applications. It covers a diverse range of topics including: bioanalytical applications (immunoassay, state of phosphorylation, metallo-drugs); environmental applications (drinking water, groundwater, seawater, speciation); reaction cells and collision cells (theory and applications); archaeology; laser ablation; isotope ratio analysis; and the performance, characterization and applications of multicollector instruments. Written by international contributors who emphasize their current perceptions and understanding of the subject, Plasma Source Mass Spectrometry: Applications and Emerging Technologies offers a current perspective on elemental analysis by plasma source mass spectrometry that is not to be found elsewhere. Researchers and professionals in many areas will welcome this book, particularly those in the fields of bioanalytical, environmental and geological chemistry.

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Plasma Source Mass Spectrometry Applications and Emerging Technologies

The Royal Society of Chemistry

Contents

1. Bio-Analytical Applications, 
Simultaneous Quantitation of Specific Proteins Using ImmunoAssay ICP-MS Zoë A. Quinn, Vladimir I. Baranov and Scott D. Tanner, 3, 
New Challenges For ICP-MS Instrumentation and Data Acquisition. Solving Problems of Real Life Biology Vladimir I. Baranov, Zoë A. Quinn, Dmitry R. Bandura and Scott D. Tanner, 16, 
Some Applications of ICP-MS in the Pharmaceutical Industry P.S. Marshall, O. Heudi, C. Ramirez-Molina, S. Mckeown, N. Parr, S. Bains, H.N. Freeman, F. Abou-Shakra, 28, 
Quantitation of Phosphorus in Biologically Active Materials by ICP-MS Detection of P and S with Chemical Resolution Dmitry R. Bandura, Vladimir I. Baranov, Olga I. Ornatsky and Zoë A. Quinn, 43, 
Application of Sector-Field ICP-MS and ICP-MS with Collision Cell for Determination of Phosphorus and Iron in Proteins Sergei F. Boulyga, Carola Pickhardt, J. Susanne Becker, Michael Przybylski and J. Sabine Becker, 54, 
Combination of ICP-MS and Ion Exchange Chromatography Permits Analyses of Specific Cisplatin DNA Modifications Formed in Cancer Cells A. Azim-Araghi, C.J. Ottley, D.G. Pearson, and M.J. Tilby, 66, 
Conventional and Chromatographic ICPMS Analysis of Cisplatin and Carboplatin in Plasma and Plasma Ultrafiltrate Robbin B. Burns and David J. Gray, 74, 
Determination, by ICP-MS, of Background and BBR 3464 Induced Levels of Platinum Bound to DNA Isolated From Blood Cells: A Comparison of the Sensitivity of the PerkinElmer SCIEX ELAN 6000 and the ThermoFinnigan Neptune Instruments T. John, C.J Ottley, D.G. Pearson, G.M. Nowell, H. Calvert and M.J. Tilby, 82, 
2. Environmental Applications, 
Applications of ICP-MS in Environmental Science Thomas Prohaska, Gunda Köllensperger, Stephan Hann, Herhard Stingeder, Walter Fitz and Walter Wenzel, 93, 
Development of "All-lum" Analytical Method for Water Samples at Lake Biwa Y. Takaku, S. Akiba, T. Hayashi, M. Kano, Y. Ohtsuka, 105, 
Iron and Arsenic Speciation in Groundwaters from West Bengal, India by Coupled HPLC-ICP-MS Utilising a Hexapole Collision Cell Andrew G. Gault, Lois E. Davidson, Paul R. Lythgoe, David A. Polya, Fadi R. Abou-Shakra, Heather J. Walker and Debashis Chatterjee, 112, 
Coupled HPLC-ICP-MS Analysis Indicates Highly Hazardous Concentrations of Dissolved Arsenic Species in Cambodian Groundwaters David A. Polya, Andrew G. Gault, Nicola J. Bourne, Paul R. Lythgoe and David A. Cooke, 127, 
An Old Problem of Lead Contamination T.D.B. Lyon, R. Ellam and C. Ramsay, 141, 
The Use of Different Enriched Isotope Mixtures for the Determination of Butyltin Compounds in Environmental Samples Using Isotope Dilution GC-ICP-MS Pablo Rodríguez-González, Jorge Ruiz Encinar, J. Ignacio García Alonso and Alfredo Sanz-Medel, 148, 
Determination of Cerium, Lead and Uranium in Bivalve Shells Using an Iminodiacetate Based Preconcentration System and ICP-MS Ted McGowan and Noel Casey, 160, 
New Applications for GC-ICP-MS; Beyond Sensitive, Selective Analysis of Organometallic Species E. McCurdy, S. Wilbur, G. Woods and D. Potter, 168, 
The Use of a High Accuracy Isotope Dilution Mass Spectrometry (IDMS) Method for the Analysis of Sulfur in Fuel to Support Analytical Technologies used in Industry R. Hearn and P. Evans, 185, 
3. Archaeological Applications, 
Anglo-Saxon Residential Mobility at West Heslerton, North Yorkshire, UK from Combined O- and Sr-Isotope Analysis. Paul Budd, Carolyn Chenery, Janet Montgomery, Jane Evans and Dominic Powlesland, 195, 
The Use of ICP-MS in Provenancing Igneous Stone Artefacts: Examples from the Southern Levant G.P. Rutter, D.G. Pearson, G. Philip, J.M.D. Day and C.J. Ottley, 209, 
4. Preparatory and Delivery Methods, 
A Routine Method for the Dissolution of Geological Samples for the Analysis of REE and Trace Elements via ICP-MS C.J. Ottley, D.G. Pearson and G.J. Irvine, 221, 
Calculation Methods for the Determination of Isotope Ratios of Transient Signals of Volatile Organometallic Compounds Silvia Wehmeier, Rob Ellam and Jörg Feldmann, 231, 
The Uncertainty in REE Determination in Urine By ETV-ICP-MS: A New Approach to Data Evaluation S. Spezia, M. Bettinelli, A. Ronchi, C. Minoia, 240, 
Trapped Ablation Mode in Laser Ablation ICPMS Experiments for the Enhancement of the Signal-To-Noise Ratio Davide Bleiner and Detlef Günther, 249, 
5. Reaction Cells and Collision Cells, 
Overcoming Spectral Overlaps: Quadrupole ICP-MS with Reaction Cell and Sector Based ICP-MS John W. Olesik and Deanna Jones, 261, 
Determination of Selenium in Biological Samples by Isotope Dilution Analysis Octapole Reaction System ICP-MS J.M. Marchante-Gayón, L. Hinojosa Reyes, J.I. García Alonso and A. Sanz-Medel, 271, 
The York University Ion-Molecule Reaction Database: A Biennial Report Gregory K. Koyanagi, Vitali V. Lavrov and Diethard K. Bohme, 282, 
Determination of Fe, Ni, Co, Cu and Zn in High-Ca Samples Using Methane as a Reaction Cell Gas Scott D. Tanner and Dmitry R. Bandura, 292, 
6. MultiCollectors, 
Long-Term Performance Characteristics of a Plasma Ionisation Multi-Collector Mass Spectrometer (PIMMS): The ThermoFinnigan Neptune G.M. Nowell, D. G. Pearson, C.J. Ottley, J. Schwieters and D. Dowall, 307, 
Chemical Pre-Concentration Procedures for High-Precision Analysis of Hf-Nd-Sr Isotopes in Geological Materials by Plasma Ionisation Multi-Collector Mass Spectrometry (PIMMS) Techniques D.P. Dowall, G.M. Nowell and D.G. Pearson, 321, 
High Precision MC-ICPMS Measurement of Silver Isotopic Compositions Sarah Woodland, Mark Rehkämper, Der-Chuen Lee and Alex N. Halliday, 338, 
Precise and Accurate Determination of Iron Isotopes by Multi-Collector Inductively Coupled Plasma Mass Spectrometry E. Mullane, S.S. Russell, M. Gounelle, T. Mason, V. Din, D. Weiss and B. Coles, 351, 
Measurement of Os Isotopes Using Plasma Ionisation Multi-Collector Mass Spectrometry and a Suggested Scheme for the Accurate Determination of Interfering Element Ratios D. G. Pearson and G.M. Nowell, 362, 
High Precision Rhenium and Platinum Isotope Dilution Analyses by Plasma Ionisation Multicollector Mass Spectrometry J.M.D. Day, D.G. Pearson and G.M. Nowell, 374, 
Uranium and Thorium Isotope Ratio Measurements Using Multiple Collector Inductively Coupled Plasma Mass Spectrometry with Multi-Ion-Counting Detectors R.M. Ellam and A. W Tudhope, 391, 
Author Index, 404, 
Subject Index, 407,