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Inhaltsangabe
Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.
Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:
- key interplay between transporters and enzymes in drug metabolism and drug interactions
- the integral role of pharmacogenetics in metabolism-based drug-drug interactions
- in vivo – in vitro correlations (reversible, mechanism-based inhibition, induction)
- in silico approaches enabling structure-activity and structure-function studies
- high-throughput screening and GLP methods for evaluating drug interactions in vitro
- the use of transgenic animal models to evaluate drug interactions
Providing helpful case examples and computer-aided modeling, Drug-Drug Interactions is filled with over 200 invaluable tables, equations, and figures to clarify key concepts, and incorporates critical new updated information.
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Über die Autorin bzw. den Autor
A. DAVID RODRIGUES is Executive Director, Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Pharmaceutical Research Institute, Princeton, NJ, and received his Ph.D. in Biochemistry from the University of Surrey, Guildford, UK. Dr. Rodrigues is a member of the American Association of Pharmaceutical Scientists and is presently serving on the Scientific Affairs Committee of the International Society for the Study of Xenobiotics. He has authored more than 75 peer-reviewed articles and over one dozen book chapters, and sits on the Editorial Board of three journals (Drug Metabolism and Disposition, Drug Metabolism Letters, and Current Drug Metabolism).
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Internationale Ausgabe
Drug-Drug Interactions, 2E, Vol 179
Internationale AusgabeAnbieter: Romtrade Corp., STERLING HEIGHTS, MI, USA
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Zustand: New. Brand New. Soft Cover International Edition. Different ISBN and Cover Image. Priced lower than the standard editions which is usually intended to make them more affordable for students abroad. The core content of the book is generally the same as the standard edition. The country selling restrictions may be printed on the book but is no problem for the self-use. This Item maybe shipped from US or any other country as we have multiple locations worldwide. Artikel-Nr. ABBB-66623