Verwandte Artikel zu AIDS Pathogenesis (Immunology and Medicine, Band 28)

AIDS Pathogenesis (Immunology and Medicine, Band 28) - Hardcover

 
9780792361961: AIDS Pathogenesis (Immunology and Medicine, Band 28)

Inhaltsangabe

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS).
The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

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Über die Autorin bzw. den Autor

Frank Miedema, PhD, is professor of Open Science, is Vice Rector for Research and chair of the Utrecht University Open Science Program. He studied biochemistry in Groningen specialising in Immunology, with a minor in the Philosophy of Science  and in 1985 obtained a PhD from the University of Amsterdam. After a career in biomedical (HIV/AIDS) research in Amsterdam, from 1985 to 2004 as Director of the Research Division of Sanquin and professor in the immunology of HIV/AIDS at AMC, he moved to UMC Utrecht where from January 2009 to March 2019 he was dean and vice chairman of the Executive Board at the University Medical Center Utrecht.

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