Multiple Drug Resistance in Cancer: Cellular, Molecular and Clinical Approaches - Hardcover

 
9780792326694: Multiple Drug Resistance in Cancer: Cellular, Molecular and Clinical Approaches

Inhaltsangabe

This book is an up-to-date review of current knowledge in the field of multiple drug resistance in human cancer. The literature up to the middle of 1993 is surveyed in specialist chapters written by different experts. Topics covered include the molecular genetics, cytogenetics and biochemistry of the mdr genes and P-glycoprotein; alternative transport proteins in MDR; topoisomerases I and II; cytochrome p450-enzymes and glutathione- S-transferases in MDR; cellular models for MDR in solid tumours and haemopoietic tumours; immunochemical and molecular biological techniques for detection of MDR-related gene expression; and clinical and pharmacological strategies to circumvent resistance. The book brings together a new combination of approaches to this serious clinical problem.

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9789401043557: Multiple Drug Resistance in Cancer: Cellular, Molecular and Clinical Approaches

Vorgestellte Ausgabe

ISBN 10:  9401043558 ISBN 13:  9789401043557
Verlag: Springer, 2012
Softcover