Over the past 15 years, there has been progressive development of a series of biophysical models for the analysis and interpretation of the cellular effects of ionizing radiation. The theme of the workshop was the development of accurate models of the interaction of radiation with tissue and the origins of carcinogenesis - probably the most important issue in the field of radiation protection, since analyses of this kind are the only alternative to epidemiological studies. This volume concentrates on physical models and data analysis, and provides the reader with indications of critical benchmark experiments which need to be included in future research.
This book will be of interest to radiation biophysicists and biologists, medical physicists and anyone involved in radiological therapy and protection, as a valuable library addition reviewing all aspects of biophysical radiation effect modelling.
Biophysical models are the analytical tools by which the effects of radiation may be interpreted, allowing assessment and prediction of the effects of low dose radiation. Many developments have taken place in modelling since the 1980s. This volume is a review of the current state of radiation effect modelling, as discussed by scientists at an international workshop held in Padua, Italy in September 1991. Research on existing models and data sets used to test different models are described in detail. The applications of models to radiation biology and radiological protection are reviewed, as are recent developments in the modelling of the carcinogenic process. The interaction of mixed radiation, trace theory and the effects of radiation on DNA are also considered. The book should be of interest to radiation biophysicsts and biologists, medical physicists and others involved in radiological therapy and protection.
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