The fourth edition of Gene Cloning is a fully revised and updated version of this most popular introductory text on the subject. This exciting new edition retains the basic structure and organisation that has proved successful for the previous three editions. Two major changes in the contents of the book are the introduction of the subject of the polymerase chain reaction (PCR) at the beginning of the book with more emphasis being placed on PCR throughout and the inclusion of a new chapter on genome sequencing and functional analysis.
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Terry Brown is Professor of Biomolecular Archaeology at the Department of Biomolecular Sciences, UMIST, Manchester, UK
The previous edition of Gene Cloning, has become known world-wide as the standard introductory text to this important and exciting subject. Now, the current importance of non-cloning approaches, notably PCR, in gene cloning has led to the creation of this fourth edition which explores DNA analysis.
Retaining the philosophy of the previous editions, Gene Cloning and DNA Analysis assumes the reader has little prior knowledge of the subject and clearly explains its importance, the principles of the techniques used and their applications. It is carefully laid out, with over 250 two-colour illustrations. In addition to some organisational changes within the re-written text, the fourth edition has two new chapters. The first covers the methods used to sequence genomes and how to understand a sequence after it has been obtained. The second looks in detail at the applications of gene cloning and DNA analysis in forensic science; providing an excellent illustration of the applications of DNA analysis in the real world.
In Gene Cloning and DNA Analysis Terry Brown has once again provided a resource of exceptional clarity, an essential introductory text to a wide range of biological sciences students, including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. Also, as well as being required reading for many course modules, it is a perfect introductory text for any professional who needs to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied or taught should have multiple copies of the book available on their shelves.
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