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Cross-over Trials in Clinical Research (Wiley Series in Statistics in Practice) - Hardcover

Buch 3 von 49: Statistics in Practice

Senn, Stephen S.

 
9780471934936: Cross-over Trials in Clinical Research (Wiley Series in Statistics in Practice)
Hardcover
ISBN 10: 0471934933 ISBN 13: 9780471934936
Verlag: John Wiley & Sons Ltd, 1992

Inhaltsangabe

An introduction to cross-over trials which studies the basic considerations and describes how such trials may be designed and analyzed. The volume features the two-stage analysis of the AB/BA design, and a number of original examples obtained from over 100 clinical trials.

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Statistics in Practice A new series of practical books outlining the use of statistical techniques in a wide range of application areas:

  • Human and Biological Sciences
  • Earth and Environmental Sciences
  • Industry, Commerce and Finance
Cross–over Trials in Clinical Research Stephen Senn Biometrics, Medical Department, CIBA–Geigy Ltd, Basle, Switzerland Cross–over Trials in Clinical Research provides a practical introduction to this important tool within the pharmaceutical industry. Aimed at guiding practitioners in the methods of using cross–over designs efficiently, this book presents a fresh insight into how such trials may be designed and analysed. Key features of this comprehensive treatment are:
  • A focus on the two–period AB/BA design, including the most up–to–date developments in this topic.
  • Important aspects of special design graphical and tabular presentation of trials, robust approaches to analysis, and practical issues in planning.
  • Direct relevance to drug development with an approach rooted firmly in biology and pharmacokinetics rather than stressing the mathematical aspects.
  • All techniques included are discussed and illustrated in detail with many practical examples drawn from the author s wide–ranging experience.
This book will prove an invaluable reference to all statisticians and researchers in the pharmaceutical industry. It will also appeal to physicians involved in clinical research.

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Verlag
John Wiley & Sons Ltd
Erscheinungsdatum
1992
Sprache
Englisch
ISBN 10 
0471934933
ISBN 13 
9780471934936
Einband
Gebundene Ausgabe
Anzahl der Seiten
296
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Verantwortliche Person
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