Biomedical Mass Transport and Chemical Reaction: Physicochemical Principles and Mathematical Modeling

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9780471656326: Biomedical Mass Transport and Chemical Reaction: Physicochemical Principles and Mathematical Modeling

TEACHES THE FUNDAMENTALS OF MASS TRANSPORT WITH A UNIQUE APPROACH EMPHASIZING ENGINEERING PRINCIPLES IN A BIOMEDICAL ENVIRONMENT INCLUDES A BASIC REVIEW OF PHYSIOLOGY, CHEMICAL THERMODYNAMICS, CHEMICAL KINETICS, MASS TRANSPORT, FLUID MECHANICS AND RELEVANT MATHEMATICAL METHODS TEACHES ENGINEERING PRINCIPLES AND MATHEMATICAL MODELLING USEFUL IN THE BROAD RANGE OF PROBLEMS THAT STUDENTS WILL ENCOUNTER IN THEIR ACADEMIC PROGRAMS AS WELL AS LATER ON IN THEIR CAREERS ILLUSTRATES PRINCIPLES WITH EXAMPLES TAKEN FROM PHYSIOLOGY AND MEDICINE OR WITH DESIGN PROBLEMS INVOLVING BIOMEDICAL DEVICES STRESSES THE SIMPLIFICATION OF PROBLEM FORMULATIONS BASED ON KEY GEOMETRIC AND FUNCTIONAL FEATURES THAT PERMIT PRACTICAL ANALYSES OF BIOMEDICAL APPLICATIONS OFFERS A WEB SITE OF HOMEWORK PROBLEMS ASSOCIATED WITH EACH CHAPTER AND SOLUTIONS AVAILABLE TO INSTRUCTORS HOMEWORK PROBLEMS RELATED TO EACH CHAPTER ARE AVAILABLE FROM A SUPPLEMENTARY WEBSITE (<HTTP://ENGINEERING.CASE.EDU/BMTR). THESE PROBLEMS PROVIDE PRACTICE IN BASIC COMPUTATIONS, MODEL DEVELOPMENT, AND SIMULATIONS USING ANALYTICAL AND NUMERICAL METHODS.

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The transport and equilibrium of chemical species is at the heart of processes that occur at all levels of biological organization-molecular, cellular, and organismal. For processes as diverse as receptor-ligand interactions and respiratory gas exchange, it is the engineering principles of thermodynamics, diffusion, and reaction kinetics that provide a unique perspective for analyzing and quantifying the underlying phenomena.

This book teaches the key scientific and engineering principles that are necessary to understand how important molecules in the human body, such as nutrients, drugs, and toxic substances, move from cell to cell, organ to organ, and between a person and the surrounding environment. It also contains information about the design of man-made devices, such as artificial lungs and kidneys, which are used in the diagnosis and treatment of human diseases.

The approach is unique in that it stresses engineering principles rather than specific applications (though applications are detailed in the latter portion of the book) and reinforces learning with diverse example problems and frequent homework assignments. This empowers students with the self-confidence necessary to successfully tackle new problems throughout their careers.

Klappentext:

Teaches the fundamentals of mass transport and chemical reaction with a unique approach emphasizing engineering principles in a biomedical environment

The impact of engineering on medicine and biology has grown significantly. Not only has this resulted in an impressive world-wide increase in educational biomedical engineering programs, but many traditional chemical and agricultural engineering departments have changed their names to include "bio-" recognizing the importance of biomedical engineering research and development to human welfare and the global economy.

Biomedical Mass Transport and Chemical Reaction is designed for students whose educational emphasis involves physicochemical aspects of biomedical systems. A major objective of this textbook is to integrate engineering principles with relevant biomedical applications at the cellular, tissue, organ, and whole-body levels. These applications incorporate basic as well as more sophisticated and complex concepts, which are appropriate for graduate as well as advanced undergraduate engineering students.

Divided into seven parts Biomedical Mass Transport and Chemical Reaction features:

  • Basic biological and modelling concepts
  • An overview of the thermodynamics that relate to interfacial, membrane and chemical reaction equilibria
  • Rate equations to analyze mass diffusion and chemical reactions
  • Basic transport models in fluids and membranes
  • Multi-dimensional transport of molecules and cell population dynamics
  • Compartment models and analyses
  • Detailed models related to treatment of tissue and organ dysfunction, delivery and distribution of drugs, and interpretation of biomedical measurements

The approach is unique in that it is organized by engineering principles rather than by specific types of applications. Learning is reinforced with diverse example problems of increasing complexity. This empowers students with the self-confidence necessary to successfully tackle new problems throughout their careers.

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