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Bacterial Population Genetics in Infectious Disease - Hardcover

 
9780470424742: Bacterial Population Genetics in Infectious Disease

Inhaltsangabe

This book is a unique synthesis of the major concepts and methods in bacterial population genetics in infectious disease, a field that is now about 35 yrs old.  Emphasis is given to explaining population-level processes that shape genetic variation in bacterial populations and statistical methods of analysis of bacterial genetic data.

  • A "how to" of bacterial population genetics, which covers an extremely large range of organisms
  • Expanding area of science due to high-throughput genome sequencing of bacterial pathogens
  • Covers both fundamental approaches to analyzing bacterial population structures with conceptual background in bacterial population biology
  • Detailed treatment of statistical methods

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Über die Autorin bzw. den Autor

D. Ashley Robinson is an Associate Professor of Microbiology at The University of Mississippi Medical Center.  Her specialties include bacterial genetics, microbial evolution and antimicrobial resistance, among others.

Daniel Falush is a Research Fellow in the Department of Statistics at the University of Oxford, where he specializes in mathematical biology, particularly mathematical genetics and bioinformatics.

Edward Feil is a Reader in Microbial Evolution at University of Bath.  He studies bacterial evolution and genetic recombination as well as the biogeography of pathogenic bacteria.

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Covers both fundamental approaches to analyzing bacterial population structures with conceptual background in bacterial population biology

Population genetics is concerned with the causes and effects of genetic variation. While many books give detailed treatments of modern population genetics, for those who study bacterial pathogens, one often has to ask "How does this apply to bacteria?" What has been lacking is a book that describes the fate of genetic variation in bacterial populations and shows how one can generate and analyze bacterial genetic data from a population genetics perspective.

Bacterial Population Genetics in Infectious Disease fills this need, serving as an authoritative primer on the major concepts and methods of an extremely broad range of organisms. The first section provides perspective on the genetic and population processes that shape genetic variation in bacterial populations, as well as the statistical methods of analysis of bacterial genetic data that provide a basis for sound inference. The second section provides detailed reviews on selected important human pathogens, which illustrate the use of analytical techniques and particular evolutionary processes.

Bacterial Population Genetics in Infectious Disease is a must for students and professionals that work in the intersecting fields of genetics, microbiology, infectious diseases, epidemiology, and evolutionary biology.

Aus dem Klappentext

Covers both fundamental approaches to analyzing bacterial population structures with conceptual background in bacterial population biology

Population genetics is concerned with the causes and effects of genetic variation. While many books give detailed treatments of modern population genetics, for those who study bacterial pathogens, one often has to ask "How does this apply to bacteria?" What has been lacking is a book that describes the fate of genetic variation in bacterial populations and shows how one can generate and analyze bacterial genetic data from a population genetics perspective.

Bacterial Population Genetics in Infectious Disease fills this need, serving as an authoritative primer on the major concepts and methods of an extremely broad range of organisms. The first section provides perspective on the genetic and population processes that shape genetic variation in bacterial populations, as well as the statistical methods of analysis of bacterial genetic data that provide a basis for sound inference. The second section provides detailed reviews on selected important human pathogens, which illustrate the use of analytical techniques and particular evolutionary processes.

Bacterial Population Genetics in Infectious Disease is a must for students and professionals that work in the intersecting fields of genetics, microbiology, infectious diseases, epidemiology, and evolutionary biology.

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