All the recognized experts from Europe, U.S.A. and Japan have contributed to make this book the most comprehensive, up-to-date survey of animal models available for AIDS research. It concerns animals which can be infected by the Human Immune-deficiency Viruses, both HIV-1 and HIV-2, such as chimpanzees, rhesus monkeys, rabbits, SCID-mice reconstituted with human cells and mice transgenic for HIV. Information is also included on animals harbouring their own variants of HIV such as cats, non-human primates and bovines. Other retrovirus models, including lentivirus viruses like Equine Infectious Anemia Virus (EIAV), Visna-Maedi, Simian Retrovirus (SRV) and Feline Leukemia Virus (FeLV) are discussed. The book also deals with the biohazard aspects of working with these viruses, the comparative value of the models and their relation with AIDS in humans. Examples of the applications of these models in the development of antiretroviral agents and vacines are given.
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