New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms: Current Research and Future Trends in Microbial Biofilms - Softcover

Über die Autorinnen und Autoren

Dr. Mukesh Kumar Yadav is working as Research Professor at Korea University College of Medicine, Seoul, South Korea. He has more than 10 years of research experience in the field of microbiology in general and molecular microbiology, molecular diagnostic, medical microbiology, Host-pathogen interaction, microbial biofilms and plant-pathology in particular. Dr. Yadav’s research is focused on microbial biofilms in clinical setups. He is particularly interested on biofilm related pathogenesis and identification of novel pathway for the development of new antimicrobial/antibiofilm compounds. The host-response during single species or multi-species colonization in vivo is also important part of his study. Using in vitro biofilm model and in vivo colonization models, his group have identified a number of natural and synthetic compounds that are effective in controlling bacterial growth in planktonic as well as under biofilm state. Treatment of biofilm related infections is huge challenge in clinical settings, and it is further complicated by emergency of antimicrobial strains. Therefore, Dr Yadav’s group is identifying non-antibiotic antimicrobial agents with multiple mode of action. Dr. Yadav has completed four major research projects on microbial biofilms funded by Korean Government under National Research Fellowship Program, and Science and Technology department (Government of South Korea). Dr. Yadav has enough exposure in the field of bacterial and fungal biofilms, and has established good collaboration with medical healthcare practitioners and industrial researchers.
Dr. Yadav’s research group has identified biofilm related genes and their pathway in both bacteria and fungi. And have identified the potential anti-biofilm compounds (synthetic and natural), and also studied genomic, proteomics and mechanism of biofilm formation by single species and multi-species using in vitro and in vivo models. Dr Yadav has published more than 35 research articles on in peer review journals.

Dr. Singh is working as a Professor and Head, Department of Agriculture and Environmental Sciences at National Institute of Food Technology Entrepreneurship and Management (NIFTEM), Kundli, Haryana, India, and has more than 20 years of experience in applied microbiology with a special focus on endophytic microorganisms and their applications in agriculture and health sciences. Dr. Singh explored the indigenous fermented products of Northeast India and isolated several probiotic strains, and characterized them. Currently, his group is exploring these isolated strains for their potential to synthesize neurotransmitters such as GABA, serotonin, dopamine, and SCFAs, and incorporating these strains into functional beverages by adopting co-encapsulation technology. Dr. Singh has published more than 100 research articles and is a part of the Global Burden of Diseases collaborators. Dr. Singh edited 8 books with Elsevier and Springer on different aspects of applied microbiology.

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Microbial Biofilms: Current Research and Future Trends is divided into three sections: Microbial adhesion/biofilms in medical settings; Microbial adhesion/biofilms in agriculture; and microbial adhesion/ biofilm in environment and industry. In the first section the adhesion and biofilm formation by pathogenic microbes on tissue and on indwelling medical devices is described and reviewed. Key aspects covered include the biofilm related human infections, microbial communication during biofilm mode of growth, host defense and antimicrobial resistance, host-response to microbial biofilms, single and multi-species biofilm infections, biofilms study models, modification of medical devices, control of microbial biofilms. In the second section the biofilms of agriculturally important microbes and environmental friendly microbes is described and reviewed. Key aspects covered include the biofilm formation on plants, in soil, and in aquatic environment. The last section of this book provides up-to-date review of the latest scientific research on microbial adhesion and biofilm formation in the environment and in industries. Key aspects covered include the biofilm formation in environment and utilization of adherent microbial community in environmental pollution control. Few chapters covered biofilms in food industry and factors affecting the biofilms growth and control strategy.