Lipid Nanoparticles-Based mRNA Delivery System - Softcover

 
9780443450068: Lipid Nanoparticles-Based mRNA Delivery System
Softcover
ISBN 10: 0443450064 ISBN 13: 9780443450068
Verlag: Academic Press, 2026

Inhaltsangabe

Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration―such as intravenous, oral, transdermal, and intranasal delivery.

The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

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Über die Autorin bzw. den Autor

Dr. Raj Kumar has a strong academic and research background in lipid-based nanocarriers and their applications in drug delivery. His work has focused on designing, synthesizing, and characterizing various nanocarriers for advanced therapeutic solutions, such as lipid, polymeric, mucoadhesive, and stimuli ROS-responsive nanoparticles. This foundational expertise enables him to critically assess the field's emerging trends, challenges, and innovations.

Von der hinteren Coverseite

Advancements in mRNA-based therapeutics have transformed the landscape of modern medicine, particularly in vaccine development and gene therapy. However, the challenge of effectively delivering mRNA to target cells remains a significant barrier to widespread clinical application. Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. This book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration―such as intravenous, oral, transdermal, and intranasal delivery. It also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. The final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field. By bringing together contributions from leading experts across the globe, Lipid Nanoparticles-Based mRNA Delivery System not only enhances understanding of lipid-based delivery technologies but also fosters collaboration and innovation in the development of mRNA therapies. This book serves as a tool for advancing the field, ultimately contributing to the broader adoption of mRNA therapeutics in clinical practice and improving patient outcomes worldwide.

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Verlag
Academic Press
Erscheinungsdatum
2026
Sprache
Englisch
ISBN 10 
0443450064
ISBN 13 
9780443450068
Einband
Taschenbuch
Anzahl der Seiten
348
Herausgeber
Kumar
Kontakt zum Hersteller
Academic Press
https://shop.elsevier.com/

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