Tic Disorders and Tourette Syndrome (Volume 215) (Handbook of Clinical Neurology, Volume 215) - Hardcover

Über die Autorinnen und Autoren

Dr. Christos Ganos is a staff neurologist at UHN’s Krembil Brain Institute, Toronto Western Hospital, and an Associate Professor in the Division of Neurology at the University of Toronto, where he also holds the Wolf Family Chair in Neurodevelopmental Psychiatry. Born in Thessaloniki, Greece, he completed his medical training at the University Medical Center Hamburg-Eppendorf in Germany, followed by a three-year fellowship at the National Hospital for Neurology and Neurosurgery in London, and from 2017 to 2023 was a consultant in the Movement Disorder Unit at Charité – Universitätsmedizin Berlin. He specializes in hyperkinetic, neuropsychiatric, and rare or unusual movement disorders, with a particular focus on tic disorders. His research centers on the detailed characterization of clinical phenomena, the elucidation of their underlying pathophysiology, and the development and implementation of novel treatments. He is the founding chair of both the Tic Disorders Study Group and the Task Force on Tic Disorders of the International Parkinson and Movement Disorder Society (MDS).

Yulia Worbe is a tenured Professor of Clinical Neurophysiology at Sorbonne University and serves as a consultant neurophysiologist and neurologist at Sorbonne University Hospitals, primarily at Pitié-Salpêtrière and Saint-Antoine. She specializes in the neurophysiology of movement disorders and has a longstanding interest in Tourette syndrome.

Dr. Worbe graduated from the Medical University of St. Petersburg, Russia, where she completed her general neurology training. She subsequently specialized in movement disorders at Pitié-Salpêtrière Hospital in Paris. Her research on Gilles de la Tourette syndrome led to a PhD in Neuroscience from Sorbonne University, where she developed animal models of Tourette disorder.

She completed two post-doctoral fellowships: one at Sorbonne University, focusing on basal ganglia and network dysfunction in Tourette disorder using neuroimaging, and another at the University of Cambridge's Behavioural and Clinical Neuroscience Institute, exploring serotonergic regulation of behavior using brain imaging.

Prof. Worbe’s research centers on the cognitive and behavioral aspects of movement disorders, with a focus on Gilles de la Tourette syndrome and genetic dystonia. She investigates brain function in these disorders using cognitive testing, neuroimaging, and non-invasive neurostimulation techniques.

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Tic Disorders and Tourette Syndrome provides a comprehensive overview of the clinical aspects, treatments, and research on tic disorders and Tourette syndrome. Clinical aspects span primary to secondary and functional tics and their differential diagnosis. Subsequent chapters discuss common neuropsychiatric comorbidities including obsessive-compulsive disorder, ADHD, mood disorders, intermittent explosive disorder, and others. Subsequent sections cover epidemiology, etiology, and pathophysiology of tics, treatment of tics, and clinical scales to evaluate tics and how to utilize these scales in the context of specific treatments. Video accompaniment shows clinical presentations, and animal models. The volume provides introductory accessible knowledge for neurologists, psychiatrists, neuropsychiatrists and psychologists, but also expert up-to-date knowledge for the advanced reader