Inhaltsangabe
Focusing on the development of enzyme inhibitors as therapeutic drugs, this textbook provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce the reader to the structure, functions, mechanisms and kinetics of enzymes, including the use of enzymes as disease markers, ytical reagents and their use in industrial processes. Subsequent chapters discuss the different types of enzyme inhibitors and the basic principles involved in developing them into an effective drug, from discovery of the lead compound to their use in the clinic. An extremely useful text for all students of pharmacy and medicinal chemistry.
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