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Nicotine and Related Alkaloids: Absorption, distribution, metabolism and excretion - Hardcover

 
9780412557408: Nicotine and Related Alkaloids: Absorption, distribution, metabolism and excretion
Hardcover
ISBN 10: 0412557401 ISBN 13: 9780412557408
Verlag: Springer, 1993

Inhaltsangabe

Plant metabolism. Mammalian metabolism: overview. Nicotine to cotinine. Nicotine to cotinine: enzyme induction. N-oxidation, N-methylation and conjugation reactions. Nicotine metabolism: beyond cotinine. Extrahepatic nicotine metabolism. Minor tobacco alkaloids. Pharmacokinetics of nicotine and metabolites in animals. Pharmacokinetics of nicotine and metabolites in humans. Factors influencing individual variation in nicotine pharmacokinetics. Analysis of nicotine. Chromatographic analysis of nicotine and metabolites. Nicotine and metabolites: pharmacokinetics models. New methods for probing the in vivo disposition of nicotine in humans. Aspects of metabolism of S- nicotine.

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Críticas

the editors have done an excellent job in providing an update on the important issues of the biosynthesis, distribution, metabolism and excretion of nicotine... well referenced.... the quality of the figures and tables is very good... overall, this is an excellent review of the area, good value for money, fills a gap in the literature and I am sure will serve as the prime reference source for several years to come - Xenobiotica; The book, which is indexed, well edited and well produced, constitutes a state-of-the-art benchmark ... - Journal of Applied Toxicology

Reseña del editor

This is an essential reference volume for anyone interested in nicotine and tobacco. An international team of authors contribute to this comprehensive review of current knowledge of the pharmacokinetics and metabolism of nicotine.

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Verlag
Springer
Erscheinungsdatum
1993
Sprache
Englisch
ISBN 10 
0412557401
ISBN 13 
9780412557408
Einband
Tapa dura
Anzahl der Seiten
320
Herausgeber
Wahren J., Gorrod J.W.
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