Probability Models for DNA Sequence Evolution (Probability and Its Applications) - Hardcover

Buch 6 von 35: Probability and Its Applications

Durrett, Rick

 
9780387954356: Probability Models for DNA Sequence Evolution (Probability and Its Applications)
Hardcover
ISBN 10: 038795435X ISBN 13: 9780387954356
Verlag: Springer, 2002

Inhaltsangabe

"What underlying forces are responsible for the observed patterns of variability, given a collection of DNA sequences?" In approaching this question a number of probability models are introduced and anyalyzed.Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies that illustrate the use of these results.

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How is genetic variability shaped by natural selection, demographic factors, and random genetic drift? To approach this question, we introduce and analyze a number of probability models beginning with the basics, and ending at the frontiers of current research. Throughout the book, the theory is developed in close connection with examples from the biology literature that illustrate the use of these results. Along the way, there are many numerical examples and graphs to illustrate the conclusions.

This is the second edition and is twice the size of the first one. The material on recombination and the stepping stone model have been greatly expanded, there are many results form the last five years, and two new chapters on diffusion processes develop that viewpoint. This book is written for mathematicians and for biologists alike. No previous knowledge of concepts from biology is assumed, and only a basic knowledge of probability, including some familiarity with Markov chains and Poisson processes. The book has been restructured into a large number of subsections and written in a theorem-proof style, to more clearly highlight the main results and allow readers to find the results they need and to skip the proofs if they desire. 

Rick Durrett received his Ph.D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of eight books and 160 research papers, most of which concern the use of probability models in genetics and ecology. He is the academic father of 39 Ph.D. students and was recently elected to the National Academy of Science.

 

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Verlag
Springer
Erscheinungsdatum
2002
Sprache
Englisch
ISBN 10 
038795435X
ISBN 13 
9780387954356
Einband
Gebundene Ausgabe
Anzahl der Seiten
241
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
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