Design and Analysis of DNA Microarray Investigations (Statistics for Biology and Health) - Hardcover

Buch 10 von 69: Statistics for Biology and Health

Wright, George W.; McShane, Lisa M.; Simon, Richard M.

 
9780387001357: Design and Analysis of DNA Microarray Investigations (Statistics for Biology and Health)
Hardcover
ISBN 10: 0387001352 ISBN 13: 9780387001357
Verlag: Springer, 2004

Inhaltsangabe

The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It provides a review of available methods and presents it in a manner that is intelligible to biologists. It offers an understanding of the design and analysis of experiments utilizing microarrays to benefit scientists. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.

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This book is targeted to biologists with limited statistical background and to statisticians and computer scientists interested in being effective collaborators on multi-disciplinary DNA microarray projects. State-of-the-art analysis methods are presented with minimal mathematical notation and a focus on concepts. This book is unique because it is authored by statisticians at the National Cancer Institute who are actively involved in the application of microarray technology.

Many laboratories are not equipped to effectively design and analyze studies that take advantage of the promise of microarrays. Many of the software packages available to biologists were developed without involvement of statisticians experienced in such studies and contain tools that may not be optimal for particular applications. This book provides a sound preparation for designing microarray studies that have clear objectives, and for selecting analysis tools and strategies that provide clear and valid answers. The book offers an in depth understanding of the design and analysis of experiments utilizing microarrays and should benefit scientists regardless of what software packages they prefer. In order to provide all readers with hands on experience in data analysis, it includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is freely available from the National Cancer Institute for non-commercial use.

The authors are current or former members of the Biometric Research Branch at the National Cancer Institute. They have collaborated on major biomedical studies utilizing microarrays and in the development of statistical methodology for the design and analysis of microarray investigations. Dr. Simon, chief of the branch, is also the architect of BRB-ArrayTools.

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Verlag
Springer
Erscheinungsdatum
2004
Sprache
Englisch
ISBN 10 
0387001352
ISBN 13 
9780387001357
Einband
Tapa dura
Anzahl der Seiten
232
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Deutschland

Weitere beliebte Ausgaben desselben Titels

9781441918024: Design and Analysis of DNA Microarray Investigations (Statistics for Biology and Health)

Vorgestellte Ausgabe

ISBN 10:  1441918027 ISBN 13:  9781441918024
Verlag: Springer, 2011
Softcover