Challenges common beliefs that human potential is largely determined by genetics and other biological factors, drawing on a variety of scientific disciplines to explain how to tap innate abilities that have been influenced by environmental factors.
Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.
DAVID SHENK is the national bestselling author of five previous books, including The Forgetting, Data Smog, and most recently, The Immortal Game. He is a correspondent for TheAtlantic.com, and has contributed to National Geographic, Slate, The New York Times, Gourmet, Harper’s, The New Yorker, NPR, and PBS.
chapter one
Genes 2.0
How Genes Really Work
Contrary to what we’ve been taught, genes do not determine physical and character traits on their own. Rather, they interact with the environment in a dynamic, ongoing process that produces and continually refines an individual.
The sun begins to rise over an old river town, and through a fifth- floor window of University Hospital, a newborn cries out her own birth announcement. Her new, already sleep-deprived parents hold her tightly and simply stare, partly in disbelief that this has actually happened, partly in awe of what lies ahead. As she develops, who will she look like? What will she be like? What will be her strengths, her weaknesses? Will she change the world or just scrape by? Will she run a quick mile, paint a new idea, charm her friends, sing for millions? Will she have any talent for anything?
Only the years will tell. For right now, the parents don’t really need to know the final outcome—they just need to know what sort of difference they can make. How much of their newborn daughter’s personality and abilities are already predetermined? What portion is still up for grabs? What ingredients can they add, and what tactics should they avoid?
The fuzzy mix of hope, expectation, and burden begins . . .
TONY SOPRANO: And to think [I’m] the cause of it.
DR. MELFI: How are you the cause of it?
TONY SOPRANO: It’s in his blood, this miserable fucking existence. My rotten fucking putrid genes have infected my kid’s soul. That’s my gift to my son.
Genes can be scary stuff if you don’t understand them. In 1994, psychologist Richard Herrnstein and policy analyst Charles Murray warned in their bestselling book The Bell Curve that we live in an increasingly stratified world where the “cognitive elite”—those with the best genes—are more and more isolated from the cognitive/genetic underclass. “Genetic partitioning,” they called it. There was no mistaking their message:
The irony is that as America equalizes the [environmental] circumstances of people’s lives, the remaining differences in intelligence are increasingly determined by differences in genes . . . Putting it all together, success and failure in the American economy, and all that goes with it, are increasingly a matter of the genes that people inherit.
Stark and terrifying—and thankfully quite mistaken. The authors had fundamentally misinterpreted a number of studies, becoming convinced that roughly 60 percent of each person’s intelligence comes directly from his or her genes. But genes don’t work that way. “There are no genetic factors that can be studied independently of the environment,” explains McGill University’s Michael Meaney. “And there are no environmental factors that function independently of the genome. [A trait] emerges only from the interaction of gene and environment.”
While Herrnstein and Murray adhered to a particular ideological agenda, they also seem to have been genuinely hobbled in their analysis by a common misunderstanding of how genes work. We’ve all been taught that we inherit complex traits like intelligence straight from our parents’ DNA in the same way we inherit simple traits like eye color. This belief is continually reinforced by the popular media. As an illustration, USA Today recently explained heredity in this way:
Think of your own genetic makeup as the hand of cards you were dealt at conception. With each conception in a family comes a new shuffling of the deck and a new hand. That’s partly why little Bobby sleeps through the night as a baby, always behaves and seems to love math, while brother Billy is colicky, never listens and already is the head of a gang in kindergarten.
Genes dictate. Genes instruct. Genes determine. For more than a century, this has been the widely accepted explanation of how each of us becomes us. In his famous pea-plant experiments of the 1850s and ’60s, Gregor Mendel demonstrated that basic traits like seed shape and flower color were reliably passed from one generation to the next through dominant and recessive “heritable factors” (Mendel’s phrase before the word “gene” was introduced). After eight years and twenty- eight thousand plants, Mendel had proved the existence of genes—and seemed to prove that genes alone determined the essence of who we are. Such was the unequivocal interpretation of early-twentieth- century geneticists.
That notion is with us still. “Genes set the stage,” affirms USA Today. The environment has an impact on all of our lives, to be sure, but genes come first; they set specific lower and upper limits of each person’s potential abilities. Where did your brother get that amazing singing voice? How did you get so tall? Why can’t I dance? How is she so quick with numbers?
“It’s in the genes,” we say.
That’s what The Bell Curve authors thought, too. None of these writers realized that over the last two decades Mendel’s ideas have been thoroughly upgraded—so much so that one large group of scientists now suggests that we need to wipe the slate clean and construct an entirely new understanding of genes.
This new vanguard is a loose-knit group of geneticists, neuroscientists, cognitive psychologists, and others, some of whom call themselves developmental systems theorists. I call them interactionists because of their emphasis on the dynamic interaction between genes and the environment. Not all of the interactionists’ views have yet been fully accepted, and they freely acknowledge their ongoing struggle to articulate the full implications of their findings. But it already seems very clear that these implications are far-reaching and paradigm-shifting.
To understand interactionism, you must first try to forget everything you think you know about heredity. “The popular conception of the gene as a simple causal agent is not valid,” declare geneticists Eva Jablonka and Marion Lamb. “The gene cannot be seen as an autonomous unit—as a particular stretch of DNA which always produces the same effect. Whether or not a length of DNA produces anything, what it produces, and where and when it produces it may depend on other DNA sequences and on the environment.”
Though Mendel couldn’t detect it with his perfectly calibrated pea- plant hybrids, genes are not like robot actors who always say the same lines in the exact same way. It turns out that they interact with their surroundings and can say different things depending on whom they are talking to.
This obliterates the long-standing metaphor of genes as blueprints with elaborate predesigned instructions for eye color, thumb size, mathematical quickness, musical sensitivity, etc. Now we can come up with a more accurate metaphor. Rather than finished blueprints, genes— all twenty-two thousand of them1—are more like volume knobs and switches. Think of a giant control board inside every cell of your body.
Many of those knobs and switches can be turned up/down/on/off at any time—by another gene or by any minuscule environmental input. This flipping and turning takes place constantly. It begins the moment a child is conceived and doesn’t stop until she takes her last breath. Rather than giving us hardwired instructions on how a trait must be expressed, this process of gene-environment interaction drives a unique developmental path for every unique individual.
The new interactionists call it “GxE” for short. It has become central to the understanding of all genetics. Recognition of GxE means that we now realize that genes powerfully...
„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.
Anbieter: World of Books (was SecondSale), Montgomery, IL, USA
Zustand: Good. Item in good condition. Textbooks may not include supplemental items i.e. CDs, access codes etc. Artikel-Nr. 00098522437
Anzahl: 4 verfügbar
Anbieter: World of Books (was SecondSale), Montgomery, IL, USA
Zustand: Good. Good condition ex-library book with usual library markings and stickers. Artikel-Nr. 00108386844
Anzahl: 1 verfügbar
Anbieter: World of Books (was SecondSale), Montgomery, IL, USA
Zustand: Very Good. Item in very good condition! Textbooks may not include supplemental items i.e. CDs, access codes etc. Artikel-Nr. 00105652161
Anzahl: 2 verfügbar
Anbieter: BooksRun, Philadelphia, PA, USA
Hardcover. Zustand: Very Good. First Edition. With dust jacket. It's a well-cared-for item that has seen limited use. The item may show minor signs of wear. All the text is legible, with all pages included. It may have slight markings and/or highlighting. Artikel-Nr. 0385523653-8-1-29
Anzahl: 1 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Artikel-Nr. 2303855-6
Anzahl: 1 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Good. Former library copy. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Artikel-Nr. 2303856-6
Anzahl: 2 verfügbar
Anbieter: Better World Books: West, Reno, NV, USA
Zustand: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Artikel-Nr. 2303855-6
Anzahl: 1 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Very Good. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Artikel-Nr. 4196943-6
Anzahl: 1 verfügbar
Anbieter: Better World Books, Mishawaka, IN, USA
Zustand: Very Good. Former library copy. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Includes library markings. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good. Artikel-Nr. GRP73096055
Anzahl: 3 verfügbar
Anbieter: Wonder Book, Frederick, MD, USA
Zustand: Very Good. Very Good condition. Very Good dust jacket. A copy that may have a few cosmetic defects. May also contain light spine creasing or a few markings such as an owner's name, short gifter's inscription or light stamp. Bundled media such as CDs, DVDs, floppy disks or access codes may not be included. Artikel-Nr. X09B-00723
Anzahl: 1 verfügbar