Mitochondria as a Key Intracellular Target of Thallium Toxicity - Softcover

Über die Autorin bzw. den Autor

Sergey Korotkov is a Leading Researcher in the Laboratory of Inorganic Ions’ Biochemistry at the Sechenov Institute of Evolutionary Physiology and Biochemistry. He graduated from the Chemical Department of St. Petersburg State University in 1979 and defended his PhD thesis at Russian Academy of Sciences in 1987.

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The increase in human contact with the toxic trace element thallium is associated with the development of industry, the release of this metal into the environment from various rocks and the use of special isotope techniques for studying the vascular bed. Mitochondria as a Key Intracellular Target of Thallium Toxicity lists the pathways and mechanisms of thallium transport into cells and mitochondria. This toxicity has been analyzed at both the cellular and subcellular levels.

Mitochondria as a Key Intracellular Target of Thallium Toxicity presents a new hypothesis explaining the decrease in the antioxidant defense in the case of thallium poisoning and proposes a new model for studying the transport of inorganic cations across the inner mitochondrial membrane. Readers can expect to learn about the toxicity of thallium and its compounds, the toxicology of thallium, the toxic thallium effects on cells, and the effects of thallium on mitochondria.