Oxidative Stress: Its Mechanisms, Impacts on Human Health and Disease Onset: Its Mechanisms and Impacts on Human Health and Disease Onset - Softcover

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Dr. Harold I. Zeliger holds a PhD in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger’s research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.

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Oxidative Stress: Its Mechanisms and Impacts on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation. The book is organized in four parts. Part I, "Oxidative Stress and Disease," provides an introduction and discusses the causes of oxidative stress and the types of chemical exposures and environmental factors that precipitate disease. Part II, "Mechanisms of Oxidative Stress Driven Disease," delves into topics such as disease hallmarks and biomarkers, disease clusters, disease co-morbidities, and free radical attacks at the cellular level. Part III, "Disease Onset Prediction," describes the Oxidative Stress Index, the premise of this tool, and how it can be used to identify the primary causes of specific diseases and predict likelihood of disease onset. Part IV, "Prevention," covers oxidative stress control, maintaining essential levels antioxidants, and prevention of global warming-caused elevation of oxidative stress and disease.

With comprehensive coverage of not only the impact of OS due to chemical exposure but also the consequences of environmental factors, Oxidative Stress: Its Impact on Human Health and Disease Onset is a valuable resource for researchers and scientists in toxicology and environmental science, health practitioners, public health professionals, and others who wish to broaden their knowledge on this topic.