Ending Aging - Hardcover

Aubrey de Grey, Ph.D., is chairman and chief science officer of the Methuselah Foundation. His major research interests are the role and causes of all forms of cellular and molecular damage in mammalian aging, and the design of interventions to reverse the age-related accumulation of such damage. He has published extensively on these and other areas of gerontology. He is also editor-in-chief of the high-impact journal Rejuvenation Research, the only peer-reviewed academic periodical focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation’s growing sponsorship of SENS research worldwide.
 
Michael Rae is Dr. de Grey’s research assistant. He is the author of several scientific articles and commentaries in peer-reviewed scientific journals. He is a longtime member and onetime board member of the Calorie Restriction Society, a main contributor to the society’s “How-to Guide,” and a core scientific investigator with the society’s Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.

Aubrey de Grey, Ph.D., is chairman and chief science officer of the Methuselah Foundation. His major research interests are the role and causes of all forms of cellular and molecular damage in mammalian aging, and the design of interventions to reverse the age-related accumulation of such damage. He has published extensively on these and other areas of gerontology. He is also editor-in-chief of the high-impact journal Rejuvenation Research, the only peer-reviewed academic periodical focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation's growing sponsorship of SENS research worldwide.

Michael Rae is Dr. de Grey's research assistant. He is the author of several scientific articles and commentaries in peer-reviewed scientific journals. He is a longtime member and onetime board member of the Calorie Restriction Society, a main contributor to the society's "How-to Guide," and a core scientific investigator with the society's Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.

People alive today could live to be a thousand years old

"His clarion call to action is the message neither of a madman nor a bad man, but of a brilliant, beneficent man of goodwill, who wants only for civilization to fulfill the highest hopes he has for its future."
--Dr. Sherwin Nuland, clinical professor of surgery at Yale University School of Medicine and author of How We Die and The Art of Aging

"Seems to me this man could be put in jail with reasonable cause."
--Dr. Martin Raff, emeritus professor of biology at University College London and coauthor of Molecular Biology of the Cell

A leading researcher sketches the real "fountain of youth"

- The most realistic way to combat aging is to rejuvenate the body at the molecular and cellular level, removing accumulated damage and restoring us to a biologically younger state.
- Comprehensive rejuvenation therapies can feasibly postpone age-related frailty and disease indefinitely, greatly extending our lives while eliminating, rather than lengthening, the period of late-life frailty and debilitation.
- A comprehensive panel of rejuvenation therapies could probably be validated in laboratory mice within a decade. We would then have a good chance of developing it for human use only a decade or two thereafter.
- Removing the causes of aging-related deaths will also eliminate all the suffering that aging inflicts on most people in the last years of their lives.
- Aging kills 100,000 people a day: old people, yes, but old people are people too. Social concerns about the effects of defeating aging are legitimate but don't outweigh the merits of saving so many lives and alleviating so much suffering.