Scaling Up Treatment for the Global AIDS Pandemic: Challenges and Opportunities - Softcover

Inhaltsangabe

An estimated forty million people carry the human immunodeficiency virus (HIV), and five million more become newly infected annually. In recent years, many HIV-infected patients in wealthy nations have enjoyed significantly longer, good-quality lives as a result of antiretroviral therapy (ART). However, most infected individuals live in the poorest regions of the world, where ART is virtually nonexistent. The consequent death toll in these regions―especially sub-Saharan Africa―is begetting economic and social collapse.

To inform the multiple efforts underway to deploy antiretroviral drugs in resource-poor settings, the Institute of Medicine committee was asked to conduct an independent review and assessment of rapid scale-up ART programs. It was also asked to identify the components of effective implementation programs.

At the heart of the committee's report lie five imperatives:

• Immediately introduce and scale up ART programs in resource-poor settings.
• Devise strategies to ensure high levels of patient adherence to complicated treatment regimens.
• Rapidly address human-resource shortages to avoid the failure of program implementation.
• Continuously monitor and evaluate the programs to form the most effective guidelines and treatment regimens for each population.
• Prepare to sustain ART for decades.

• Front Matter
• Executive Summary
• 1 Introduction
• 2 Opportunities and Challenges
• 3 Lessons Learned
• 4 Principles of Scale-Up
• 5 Managing Scale-Up of Antiretroviral Therapy
• 6 The Path Forward
• Appendix A: Information Gathering Workshop Agenda
• Appendix B: Primer on Humanimmunodeficiency Virus, Acquired Immune Deficiency Syndrome and Antiretroviral Therapy
• Appendix C: Scaling Up Antiretroviral Therapy in Resource-Limited Settings: Treatment Guidelines for a Public Health Approach
• Appendix D: Human Ethical Issues Arising in ARV Scale-Up in Resource Constrained Settings
• Appendix E: Human Resource Requirements for Scaling Up Antiretroviral Therapy in Low-Resource Countries
• Appendix F: Glossary and Acronyms
• Appendix G: Committee and Staff Biographies

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