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Lactoferrin: Structure and Function: v. 357 (Advances in Experimental Medicine and Biology) - Hardcover

 
9780306447341: Lactoferrin: Structure and Function: v. 357 (Advances in Experimental Medicine and Biology)

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The 32 papers from a September 1992 international workshop in Honolulu, bring together knowledge about the iron-binding lactoferrin protein, which has been scattered among many disciplines because its biological functions are so widely diverse. They discuss structural features such as its carbohydra

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Experimental and clinical investigators join forces to explain our current understanding of lactoferrin. Drawing on many disciplines, the front-line authorities writing here define the known structural features of lactoferrin and describe in detail several of its physiological functions. These include the role of lactoferrin in killing bacteria, and its involvement in cell growth and proliferation, in the modulation of immune function, and in iron absorption. Particular attention is given to lactoferrin functions in the regulation of normal and diseased states. New knowledge of the molecular biology of lactoferrin is also included, along with discussions of commercially viable large-scale production techniques and important new industrial applications. This comprehensive, multidisciplinary work should open the door to the greatly expanded use of lactoferrin as a bioactive reagent in foods and pharmaceuticals. Lactoferrin: Interactions and Biological Functions offers a comprehensive, multidisciplinary view of our present knowledge of lactoferrin. The book should open the way to the expanded use of lactoferrin as a bioactive reagent in foods and pharmaceuticals.

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9781461360872: Lactoferrin: Structure and Function: 357 (Advances in Experimental Medicine and Biology)

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ISBN 10:  1461360870 ISBN 13:  9781461360872
Verlag: Springer, 2012
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Verlag: Springer, 1995
ISBN 10: 0306447347 ISBN 13: 9780306447341
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Hutchens, T. William|Hutchens, T. Ed.|Lonnerdal, Bo
Verlag: SPRINGER NATURE, 1995
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T William Hutchens
Verlag: Springer Feb 1995, 1995
ISBN 10: 0306447347 ISBN 13: 9780306447341
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Buch. Zustand: Neu. Neuware - Three-Dimensional Structure of Lactoferrin in Various Functional States.- Characterization of Two Kinds of Lactotransferrin (Lactoferrin) Receptors on Different Target Cells.- Primary and Three-Dimensional Structure of Lactotransferrin (Lactoferrin) Glycans.- Synergism and Substitution in the Lactoferrins.- Salt Effects on the Physical Properties of the Transferrins.- Interaction of Lactoferrin with Sequestered Transition Metal Ions.- Bactericidal Activity of Different Forms of Lactoferrin.- The Effects of Lactoferrin on Gram-Negative Bacteria.- Faecal Flora in the Newborn: Effect of Lactoferrin and Related Nutrients.- The Monocytic Receptor for Lactoferrin and Its Involvement in Lactoferrin-Mediated Iron Transport.- Study on the Binding of Lactotransferrin (Lactoferrin) to Human PHA-Activated Lymphocytes and Non-Activated Platelets: Localisation and Description of the Receptor-Binding Site.- Physical Characteristics and Polymerization during Iron Saturation of Lactoferrin, a Myelopoietic Regulatory Molecule with Suppressor Activity.- Lactoferrin and the Inflammatory Response.- The Role of Lactoferrin as an Anti-inflammatory Molecule.- Interaction of Lactoferrin with Mononuclear and Colon Carcinoma Cells.- Lactoferrin Receptors in Intestinal Brush Border Membranes.- Maternal Lactoferrin in the Urine of Preterm Infants: Evidence for Retention of Structure and function.- Lactoferrin Gene Promoter in Human and Mouse: Analogous and Dissimilar Characteristics.- Lactoferrin cDNA: Expression and In Vitro Mutagenesis.- Antimicrobial Peptides of Lactoferrin.- Physicochemical and Antibacterial Properties of Lactoferrin and Its Hydrolysate Produced by Heat Treatment at Acidic pH.- A Comparison of the Three-Dimensional Structures of Human Lactoferrin in Its Iron Free and Iron Saturated Forms.- Bovine Lactoferrin: Isolation and Characterisation of Genomic Regulatory Sequences.- X-Ray Structural Analysis of Bovine Lactoferrin at 2.5 Å Resolution.- Binding of Porcine Milk Lactoferrin to Piglet Intestinal Lactoferrin Receptor.- Lactoferrin-Receptor Interaction: Effect of Surface Exposed Histidine Residues.- Kinetic Parameters for the Heat Denaturation of Bovine Lactoferrin in Milk, and Its Effect on Interaction with Monocytes.- Cloning and Expression of the C-Terminal Lobe of Human Lactoferrin.- Crystallographic Studies on Metal and Anion Substituted Human Lactoferrin.- Proposed Mechanisms for the Involvement of Lactoferrin in the Hydrolysis of Nucleic Acids.- Lactoferrin Promotes Nerve Growth Factor Synthesis/Secretion in Mouse Fibroblast L-M Cells.- Summary Chapter: Lactoferrin Structure and Function: Remaining Questions, Methodological Considerations and Future Directions. Artikel-Nr. 9780306447341

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