Excerpt from A Reference Handbook of the Medical Sciences, Vol. 7: Embracing the Entire Range of Scientific and Practical Medicine and Allied Science, by Various Writers
Salicin is easily prepared from willow bark by extract ing with water, precipitating tannin, etc.. With litharge, evaporating and crystallizing out the salicin, and purify ing by resolution and repetition of the process. From populin it is prepared by boiling with lime water or barium hydroxide. It can also be prepared synthetically The following is the official description: Colorless. Or white, silky, shining crystalline needles, or a crystalline powder, odorless, and having a very bit ter taste. Permanent in the air.
Soluble, at 15° C. (59° in 28 part-s of water, and in 30 parts of alcohol; in part of boiling water and in 2 parts of boiling alcohol; almost insoluble in ether or chloroform.
When heated to 198° C. F.) salicin melts, yielding a colorless liquid which, on cooling, congeals to a crystalline mass. Upon ignition, it is consumed, leav ing no residue.
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