Cell division is a central biological process: it yields the cells required for development and growth, and supplies the replacement cells to repair and maintain old or damaged tissue. But how does this cell division occur? How is it regulated? And what are the consequences when regulation fails? The second edition of The Cell Cycle: Principles of Control provides an engaging insight into the process of cell division, bringing to the student a much-needed synthesis of a subject entering a period of unprecedented growth as an understanding of the molecular mechanisms underlying cell division are revealed. The book gives the student a complete overview of the process of cell division - from chromosome duplication through mitosis, cytokinesis, and meiosis - before exploring how cell proliferation is controlled, and how the cell cycle responds to DNA damage. Finally, the book examines the intrinsic relationship between the cell cycle and cancer, and how a detailed understanding of the cell cycle may lead to new specific therapies to treat the disease. An understanding of the cell cycle is central to an understanding of biological systems and processes. The Cell Cycle: Principles of Control is the ideal resource for any student wishing to develop a sound grasp of this vitally important subject. Online Resource Centre The Online Resource Centre to accompany The Cell Cycle features: For students: * Links to useful online resources provided by research laboratories For registered adopters of the book: * Figures from the book available to download * Journal Clubs providing suggested papers and discussion questions linked to topics in the book
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David Morgan is a Professor in the Departments of Physiology and Biochemistry & Biophysics at the University of California, San Francisco, where he is a leading researcher on the mechanisms of cell cycle control. He has received awards for his teaching of cardiovascular physiology, cell biology, and biochemistry.Review:
Review from previous edition: "I have enjoyed reading this textbook cover to cover. I have learned new things from chapters that lie outside of my own specialisation of chromosome duplication, and have made interesting new connections. As a University teacher and researcher, I can strongly recommend David Morgan's textbook to students with a background in molecular biology who are interested in the regulation of the eukaryotic cell cycle." --Torsten Krude in BioEssays, June 2007
"This is an extremely useful book, which can be used in undergraduate (for an advanced course) and graduate teaching, and as a reference book for researchers in the field. The book will remain an essential source of information for curious students and scientists for some time." --Nature Cell Biology, June 2007
"an excellent reference book for cell biology undergraduates with an interest in the cell cycle and the related field of cancer research. It would also make a useful reference book for any post-graduate student in a cell-cycle laboratory." --THES Textbooks Guide, February 2007
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