The number of neurological conditions associated with the prions continues to grow. The list includes BSE and scrapie, affecting cattle and sheep respectively, and Creutzfeldt-Jakob disease, which affects humans. Prion diseases provides the most up-to-date summary of this important field, from the basic structural properties of the prion protein, through the cell biology and transgenic models of prion diseases, to the pathology of the diseases which affect animals and humans. This is an area of intense interest to neuroscientists, veterinary scientists, and clinicians. It has attracted significant media attention because of the potential risks to humans, which means that it is also of interest to policy-makers throughout the world.
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