Medicinal Chemistry: A Biochemical Approach - Hardcover

The molecular action of drugs is emphasized in this text, which has been updated to incorporate the most recent research findings of biochemical pharmacology and the latest insights into the interactions of drugs with their receptors. It is organized by targets of drug action - endogenous messengers and their receptors, membranes, enzymes, and DNA, among others - and covers all the drug groups and their therapeutic applications. This thorough revision provides expanded coverage of co-transmitters and neuro-hormones, as well as adenosine receptors and calcium channel blockers. New topics include atrial natriuretic factors, antiarrhythmic drugs, and DNA topoisomerase inhibitory mechanism of antitumour and antibacterial agents. Undergraduate students, especially in pharmacology, and pharmacy schools.