Artificial Intelligence in Bioinformatics: From Omics Analysis to Deep Learning and Network Mining - Softcover

Über die Autorinnen und Autoren

Mario Cannataro is a Full Professor of Computer Engineering and Bioinformatics at University “Magna Graecia” of Catanzaro, Italy. He is the director of the Data Analytics research center and the chair of the Bioinformatics Laboratory. His current research interests include bioinformatics, medical informatics, artificial intelligence, sentiment analysis, data analytics, parallel and distributed computing. He is a member of the editorial boards of Briefings in Bioinformatics and IEEE/ACM Transactions on Computational Biology and Bioinformatics. He was guest editor of several special issues on bioinformatics and health informatics and organized several bioinformatics workshops in conjunction with ACM-BCB and IEEE-BIBM conferences. He has published three books and more than 300 papers in international journals and conference proceedings. Prof. Cannataro is a member of the Ethical Committee of the Calabria Region and a senior member of ACM, IEEE and SIBIM, He is currently a member of the steering committee of the Italian Bioinformatics Society (BITS) and of the Italian Association for Telemedicine and Medical Informatics (AITIM).

Pietro Hiram Guzzi the Ph.D. degree in biomedical engi- neering from Magna Græcia University, Italy, in 2008. He has been an Associate Professor of computer engineering with Magna Græcia Univer- sity since 2008. He has been a Visiting Researcher with Georgia Tech University, Atlanta. He has authored two books. His research interests include semantic-based and network-based analysis of biological and clinical data. He is a member of the ACM, BITS, ISMB, and NETBIO COSI. He is an Editor of a newsletter of the ACM Special Interest Group on Bioinformatics, Computational Biology, and Biomedical Informatics (SIGBio), and the IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS. He serves the scientific community as a reviewer for many conferenceS. He wrote two books and he edited another one.

Giuseppe Agapito is an assistant professor of computer engineering with the University Magna Græcia, Catanzaro, Italy. His current research interests include analysis and visualization of biological networks, efficient analysis of genomics data, parallel computing, and data mining. In particular, the research activity is focused on the development and implementation of statistical and data mining methodologies also based on parallel and distributed computing, for the efficient analysis of omics data. He has published over 70 articles for international journals and conference proceedings. He is a member of the ACM, ACM SIGBio, and BITS.

Chiara Zucco received her Master Degree in Mathematics at the University of Calabria. She currently is a third-year Ph.D. student in the Biomarkers of Chronic and Complex Diseases Ph.D. Program at University “Magna Graecia” of Catanzaro, Italy. Her Ph.D. research is mainly focused on applying Text Mining and in particular Sentiment Analysis techniques for patient monitoring and adverse events prediction. She is also interested in Explainable Artificial Intelligence.

Marianna Milano received her Master Degree in Computer Engineering from the University "Magna Graecia" of Catanzaro, Italy, in 2011 and the Ph.D. degree in Biomarkers of Chronic and Complex Diseases at the University "Magna Graecia" of Catanzaro, Italy, in 2019. Her research interests comprise semantic-based and network-based analysis of biological and clinical data. She is a member of BITS (Italian Bioinformatics Society).

Von der hinteren Coverseite

Artificial Intelligence is used in several application domains to solve problems with improved accuracy and speed. This work reviews the main applications of Artificial Intelligence in Bioinformatics, from omics analysis, to deep learning and network mining.

A main need for a new resource in this area is related to the fact that Artificial Intelligence is mainly treated in computer science texts, where the main focus is on computational aspects. On the other hand, bioinformatics books focus mainly on bioinformatics key methods and only touch basic aspects of Artificial Intelligence, machine learning and data mining. To face those issues, the book combines a rigorous introduction of Artificial Intelligence methods in the context of bioinformatics with a deep and systematic review of how those methods are incorporated in bioinformatics tasks and processes.

This book first recalls main methods and theory behind Artificial Intelligence, including emergent fields such as Sentiment Analysis and Network Alignment. It then surveys how Artificial Intelligence is exploited in main bioinformatics applications, including sequence analysis, structure analysis, functional analysis, protein classification, omics analysis, biomarker discovery, integrative bioinformatics, protein interaction analysis, metabolic networks analysis, network embedding, ontologies, text mining, reasoning in bioinformatics and explainable models in bioinformatics.