Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications brings into one place information on the design and biomedical applications of different classes of nanoparticles. While aspects are dealt with in individual journal articles, there is not one source that covers this area comprehensively. This book fills this gap in the literature.
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Eun Ji Chung is WiSE Gabilan Assistant Professor and Assistant Professor of Biomedical Engineering at the University of Southern California, USA. Her work focuses on the he design and application of self-assembling, peptide amphiphile micelle nanoparticles for cardiovascular and cancer theranostics.
Lorraine Leon is Assistant Professor of Materials Science and Engineering, University of Central Florida, USA. Her research focuses in the areas of nanomedicine, molecular engineering and self-assembly
Carlos Rinaldi is Charles A. Stokes Term Professor & Chair, Department of Chemical Engineering and Biomedical Engineering, University of Florida, USA. His research is focused on advancing the understanding and biomedical applications of suspensions of magnetic nanoparticles.
Nanoparticles for Biomedical Applications explores a diverse range of nanoparticles in various stages of development and use in biomedicine, while also providing fundamental principles and basic knowledge for designing nanoparticles for biomedical applications.
The book covers an extensive range of nanoparticles that have shown promise for biomedical applications. Topics include the synthesis, design, characterization, functionalization, modifications, and lessons learned for nanoparticles being developed for applications in drug delivery, diagnostics, theranostics, and immunotherapy. Insights into pharmacokinetics, safety, scale-up engineering, and current challenges and barriers/future directions are also provided. Specific consideration is given to active targeting mechanisms and the ligands used, vs. passive-targeting, and success stories of currently clinically used nanomedicines.
The book offers a combination of background, theory, and examples of how state-of-the-art technologies are being used, to ensure that the applications discussed are set in their proper context. This will therefore be an important information source for both
Industrial researchers wishing to learn about new technologies that are just entering the commercialization phase.
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