The Zebrafish: Disease Models and Chemical Screens (Volume 138) (Methods in Cell Biology, Volume 138) - Hardcover

 
9780128034736: The Zebrafish: Disease Models and Chemical Screens (Volume 138) (Methods in Cell Biology, Volume 138)

Inhaltsangabe

The Zebrafish: Disease Models and Chemical Screens, Fourth Edition , the latest volume in the Methods in Cell Biology series, looks at methods for analyzing genetics, genomics, and transcriptomics of zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, developmental epigenetics, and the zebrafish interactome.

Covers sections on model systems and functional studies, imaging-based approaches, and emerging studies
Includes chapters written by experts in the field
Contains cutting-edge material on the topics discussed

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Über die Autorinnen und Autoren

Professor of Biochemistry and Marine Biology at Northeastern University, promoted 1996. Joined Northeastern faculty in 1987. Previously a faculty member in Dept. of Biochemistry at the University of Mississippi Medical Center, 1983-1987.Principal Investigator in the U.S. Antarctic Program since 1984. Twelve field seasons "on the ice" since 1981. Research conducted at Palmer Station, Antarctica, and McMurdo Station, Antarctica.Research areas: Biochemical, cellular, and physiological adaptation to low and high temperatures. Structure and function of cytoplasmic microtubules and microtubule-dependent motors from cold-adapted Antarctic fishes. Regulation of tubulin and globin gene expression in zebrafish and Antarctic fishes. Role of microtubules in morphogenesis of the zebrafish embryo. Developmental hemapoiesis in zebrafish and Antarctic fishes. UV-induced DNA damage and repair in Antarctic marine organisms.

Grousbeck Professor of Pediatrics, Boston Children's Hospital / HHMI, Boston, MA, USA

Professor, Department of Biology, Institute of Neuroscience, University of Oregon, Eugene, OR, USA

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