The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders.
Dr Niall Hyland is a Lecturer in Pharmacology & Therapeutics and a member of Faculty at the Alimentary Pharamabiotic Centre (APC) at University College Cork (UCC). Prior to returning to Ireland in 2007, his work on lower esophageal sphincter function, at Louisiana State University, had direct clinical implications for gastrointestinal disorders such as reflux disease. He subsequently completed his Ph.D in Pharmacology at Kings College London examining the functional role of neuropeptide Y receptors in the colon. From London, he moved to the University of Calgary in Canada, having obtained an AstraZeneca-supported Fellowship, to study the influence of obesity, inflammation and early-life immune challenge on intestinal physiology. His current research is focused on understanding the role of commensal organisms and putative probiotics on colonic fluid and electrolyte transport and the role of the innate immune system in functional bowel disorders. He has competitively obtained independent research support from the Health Research Board (Ireland), Science Foundation Ireland, through their support of the APC, and from Canadian Association of Gastroenterology-Canadian Institutes of Health Research. Niall has published in leading gastroenterology journals including Gut and Gastroenterology.
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