This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.
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gregory.ginsberg.uphs.upenn.edu; Patrick T. Tam [ptt1@humboldt.edu]
This book is an overview of contemporary research in the molecular and cellular aspects of mouse embryonic development. It showcases how embryological experimentation is shedding light on issues of early embryonic patterning, inductive interactions and organogenesis. The authors are all experts in mammalian development and each chapter provides an introductory overview of the field as well as more detailed current research findings.This book is aimed at investigators, from graduate students to senior scientists, who are beginning to explore the mouse as a model system for studying vertebrate development and its relevance to human disease. The mouse is becoming increasingly attractive as the major model system for the functional annotation of mammalian genome. This book provides a broad-based introductory research-based text for investigators who may be interested in incorporating the mouse into their research endeavors.
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