Cell Lineage and Fate Determination - Hardcover

 
9780125052559: Cell Lineage and Fate Determination
Hardcover
ISBN 10: 0125052553 ISBN 13: 9780125052559
Verlag: Academic Press, 1998

Inhaltsangabe

Cell Lineage and Fate Determination provides a comprehensive view of the mechanisms regulating cell lineage and fate determination in an effort to understand how the fertilized egg is transformed into a complex of specialized tissues. It presents basic information on eight different animal models and recent developmental biological research done in each model. The book provides a focused forum presenting key information for researchers studying various aspects of developmental and cellular biology. Extensive use of tables and black-and-white and color figures helps illustrate each model. The book concludes by discussing future goals for bringing cellular, molecular, and genetic research to clinical applications and tissue replacement therapies.

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Über die Autorin bzw. den Autor

Sally A. Moody is Professor of Anatomy and Cell Biology at the George Washington University Medical Center, and a member of both the Neuroscience and Genetics programs. Prior to this appointment she was on the faculty of the Anatomy and Cell Biology Department, the Department of Neuroscience, and the Developmental Biology program at the University of Virginia. She trained in developmental neurobiology at the University of Florida’s Department of Neuroscience and the University of Utah’s Department of Neurobiology and Anatomy. Dr. Moody’s current research focuses on the cascade of interactions that instruct lineages to give rise to the frog nervous system. She has taught developmental neurobiology in the MBL "Neurobiology" course and was co-director of the "Early Development of Xenopus Laevis" course at the Cold Spring Harbor Laboratory. She has also served on many National Institute of Health advisory committees dealing with issues in developmental biology and developmental neurobiology, and served on the Board of Trustees of the Society for Developmental Biology.

Von der hinteren Coverseite

Cell Lineage and Fate Determination brings together established and young investigators who are leading authorities on the determination of cell fate. Our current understanding of cell fate commitment and cell lineage determination is derived from studies of a number of different organisms, each ideally suited to elucidate particular components of the whole story. Therefore, this book is divided into sections, each representing one major animal model, in which exciting new advances in lineage and fate determination are discussed. Because few can master the intricacies and peculiarities of the development of all necessary animals, or of all critical experiments, this volume provides broad coverage of how combined research in these animals forms our current view of the mechanisms regulating cell lineage and fate. Information obtained in one model system can cross-fertilize the thinking of researchers utilizing another model system, and thus spur new approaches and hypotheses. The final section emphasizes the utility of such an approach by presenting advances in tissue determination that have been made possible by multianimal research strategies.
@introbul:Key Features:
@bul:* Each animal model (sea urchin, leech, nematode, fly, frog, fish, chick, and mammal) is presented in a separate section, beginning with an introduction that presents the salient developmental processes and the experimental usefulness of the model
* The sections on each animal model contain 3-4 research chapters addressing different issues of cell lineage and cell fate determination in that animal. These chapters provide the background, the most recent advances, and comments on the future promise and the expected applied significance of the area of research
* The final section provides examples of research areas in which results of studies of tissue differentiation have been fruitfully applied to multiple animals, and in which clinical application is close at hand
* Many color figures are included
* Numerous chapters address issues of particular interest to developmental neurobiologists

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Verlag
Academic Press
Erscheinungsdatum
1998
Sprache
Englisch
ISBN 10 
0125052553
ISBN 13 
9780125052559
Einband
Gebundene Ausgabe
Anzahl der Seiten
644
Herausgeber
Moody Sally A.
Kontakt zum Hersteller
Nicht verfügbar
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