Mims' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.
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Tony Nash is Emeritus Professor of Infectious Diseases at the University of Edinburgh. He has had a distinguished career i the field of viral pathogenesis in which he has over a 150 publications. He is a Fellow of the Royal Society of Edinburgh and of the Academy of medical sciences of the UK.
Cedric Mims began as a zoologist, studying under GP Wells and JBS Haldane at University College, London. He then went to the Middlesex Hospital Medical School, London, graduating in 1952. After hospital appointments he spent three years in Uganda studying tropical fevers, and then 16 years in Canberra, Australia, interspersed with two years in the USA. This was followed by a 20-year period in London as Professor of Microbiology at Guy's Hospital Medical School, where his enthusiasm for teaching found its outlet. His entire career has focused on infectious diseases and immunology, and he has produced five books and more than a hundred scientific papers on these subjects. He has four children and nine grandchildren and lives in the Sussex countryside.
Just as the virologist has to study not only the virus itself but also the cell and its response to infection, so the student of infectious disease must understand the body's response to infection as well as the properties of the invading microbe. An understanding of pathogenesis is vital in our continuing battle against infectious diseases and for the development of new treatment and preventative strategies.
The new revised edition of this unique and highly readable work describes the mechanisms by which invading microbes cause disease and how the body reacts in defence. Principles are clearly explained, using examples from bacterial, parasitic, viral and fungal infections.
New features include:
* Microbial gene sequencing
* Role of bacterial virulence factors in vivo
* Latest data on tuberculosis - the number one infectious disease worldwide
* Role of pathogenic cytokines
* Significance of toxins
* An update on vaccines, prions, immune evasion, microbial ligands and receptors
Now regarded as a classic, Mim's Pathogenesis of Infectious Disease continues to be essential reading for all microbiology, infectious disease, immunology and pathology students at undergraduate and postgraduate levels, medical students and those new to the field.
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