Adenosine Receptors and Parkinson's Disease (Pure and Applied Mathematics) - Hardcover

 
9780124004054: Adenosine Receptors and Parkinson's Disease (Pure and Applied Mathematics)

Inhaltsangabe

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease.

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Über die Autorin bzw. den Autor

Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinson’s disease. He has spent the major part of his career at King’s College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of King’s College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders.

Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinson’s disease patient-carer groups across the UK.

Von der hinteren Coverseite

The book is the first and, at present time, the only definitive overview on adenosine antagonists and Parkinson's disease. Coverage includes groundbreaking research on biochemistry, molecular biology, medicinal chemistry, electrophysiology, pharmacology, and neurochemistry to delineate a novel mechanism and concept of adenosine A2A receptor antagonists for the therapeutic approach to Parkinson's disease.

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Weitere beliebte Ausgaben desselben Titels

9780123911612: Adenosine Receptors and Parkinson's Disease

Vorgestellte Ausgabe

ISBN 10:  0123911613 ISBN 13:  9780123911612
Verlag: Academic Press, 2012
Softcover