Potassium Ion Channels: Molecular Structure, Function, and Diseases (Volume 46) (Current Topics in Membranes, Volume 46) - Hardcover

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Potassium ion channels are an essential component of cell excitation. Recent rapid progresses in the field of potassium ion channels have further disclosed the importance of this superfamily of membrane proteins in understanding not only many cellular functions but also human diseases. The K+ channels are involved in such physiological processes as glucose-induced secretion of insulin, deceleration of heart beat, formation of slow inhibitory postsynaptic potential in brain and secretion, absorption of potassium ions in epithelial cells and so on. Many diseases are caused by the abnormalities of potassium ion channels. They include diabetes mellitus, life-threatening hereditary cardiac arrhythmia, epilepsy, neural degeneration and renal hypertension. This volume offers the readers the comprehensive state of art of this field in the understanding of the genes, molecular structure, function, and diseases of potassium ion channels.|Potassium ion channels are an essential component of cell excitation. Recent rapid progresses in the field of potassium ion channels have further disclosed the importance of this superfamily of membrane proteins in understanding not only many cellular functions but also human diseases. The K+ channels are involved in such physiological processes as glucose-induced secretion of insulin, deceleration of heart beat, formation of slow inhibitory postsynaptic potential in brain and secretion, absorption of potassium ions in epithelial cells and so on. Many diseases are caused by the abnormalities of potassium ion channels. They include diabetes mellitus, life-threatening hereditary cardiac arrhythmia, epilepsy, neural degeneration and renal hypertension. This volume offers the readers the comprehensive state of art of this field in the understanding of the genes, molecular structure, function, and diseases of potassium ion channels.