Heuser
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Heuser, Frederick W. J.: Gerhart Hauptmann's Trip to America in 1894. (=REprinted from The Germanic Review, Vol. XIII, No. 1, January, 1938). 1938.
Good. Signed by the author. With red underlinings. Cover worn.
31 pp. One ill. Booklet
Malaclypse the Younger: Principia Discordia. Or How I Found Goddess And What I Did To Her When I Found Her. The Magnum Opiate Of Malaclypse The Younger Wherein Is Explained Absolutely Everything Worth Knowing About Absolutely Anything. [Verm. ein Raubdruck]. Bonn, Edition Discordia H. W. Heuser, 1982.
"We are proud to present the second Loompanics of the legendary underground classic Principia Discordia, the bible of Discordianism. Discordianism, based on worship of Eris, the Greek goddess of chaos and confusion, was invented by Kerry Thornley (Omar Khayyam Ravenhurst) and Greg Hill (Malaclypse the Younger) [...] For this new printing, we have added a never-before-published Introduction by Robert Anton Wilson, one of Discordianism's greatest prophets, as well as a brand new (never-before-published) Afterward by Gregg Hill, the original author. Also included is the never-before published 'Fith Edition', and a Gregg Hill collage." (Preface) - Hergestellt im Kopierverfahren, offensichtlich ein Raubdruck. Einige Seiten kopfüber. Gutes Expl.
[ca. 100 p.], 8°, O-Paperback
Noakes, Jeremy / Wende, Peter / Wright, Jonathan (ed.): Britain and Germany in Europe 1949 - 1990. Oxford, Oxford University Press/German Hist. Institute London 2002.
Mit Beiträgen von C. A. Wurm, A. S. Milward, L. Kettenacker, B. Koehler, Beatrice Heuser u.a.
Studies of the German Historical Institute London. 8°. VIII; 1 Blatt; 398 Seiten. Original-Pappband mit goldgeprägtem Rückentitel und illustriertem Original-Schutzumschlag. Name des Vorbesitzers am Vorsatz. Von sehr guter Erhaltung!
[KW: Europäische Integration; Internationale Beziehungen; Diplomatie; Westbindung]
Heuser, Florian: Increasing the Productivity of Whole Cell Biotransformation by Enhancing the intracellular NAD(H) Concentration, GRIN VERLAG, Oktober 2009, Besorgungstitel - vorauss. Lieferzeit 3-5 Tage. ISBN: 3640456327
The aim of this work was to limit the intracellular NAD turnover and to increase the intracellular NAD concentration in Escherichia coli in order to construct a strain characterized by higher productivity and improved long-term stability in the reductive whole-cell biotransformation. To this end, first the genes yrfE and yjaD were deleted, which code for the NADH-pyrophosphatases that probably play a part in intracellular NAD degradation. After deletion of these genes, the specific activity of the NADH-pyrophosphatase in the raw extract was reduced by 70%. By overexpressing the genes pncB and nadE from the NAD biosynthesis it was possible to double the intracellular NAD concentration. The joint overexpression of the two genes increased the NAD pool by a factor of seven.A recombinant strain of E. coli for obtaining mannitol from fructose was the reference system for studying whether the mutations in the NAD metabolism influenced the long-term stability of whole-cell transformations. Here, fructose was reduced to mannitol by a mannitol dehydrogenase from Leuconostoc pseudomesenteroides. The cofactor NADH was regenerated by a formate dehydrogenase from Mycobacterium vaccae N10. The uptake of fructose was made possible by a glucose facilitator from Zymomonas mobilis. In the present study, it was foand that during the biotransformation the cells lost NAD(H) via a permeabilized cell membrane. The cause of cell permeabilization was foand to be an accumulation of mannitol in the cell, which led to bursting of the cell due to increased osmotic pressure. By cloning a putative mannitol transport gene from L. pseudomesenteroides, it was possible to increase long-term productivity of the recombinant E. coli, so that after three days of biotransformation the mannitol yield was increased by 20%. Biochemical characterization revealed that the putative mannitol transporter is a secondary carrier specific for fructose.
NEUBUCH! 2009. 116 S. 2 Farbabb. 210 mm 210 mm x 148 mm x 8 mm; Akademische Schriftenreihe, Bd. V137750




