Vision: How It Works and What Can Go Wrong (The MIT Press) - Hardcover

...John and Joseph Dowling have turned the trick in their brilliant new book called Vision: How It Works and What Can Go Wrong. The Dowlings have tucked basic visual science and clinical ophthalmology into a seamless monograph that reaches from mudpuppy retinas to senile macular degeneration. Written for anyone who has ever enjoyed Scientific American or Lewis Thomas's The Lives of a Cell, it is also a volume for any molecular biologist who has never heard of amblyopia or any clinician who is unfamiliar with A2E and lysosomes. -The FASEB Journal

Descriptions of basic visual mechanisms and related clinical abnormalities, by a neuroscientist and an ophthalmologist. Over the past fifty years, enormous progress has been made in understanding visual mechanisms and treating eye disorders. And yet the scientist is not always aware of the latest clinical advances and the clinician is often not up to date on the basic scientific discoveries. Writing in nontechnical language, John and Joseph Dowling, a neuroscientist and an ophthalmologist, examine vision from both perspectives, providing concise descriptions of basic visual mechanisms and related clinical abnormalities. Thus, an account of the photoreceptors is followed by a consideration of retinitis pigmentosa and macular degeneration; an explanation of the retina's function is followed by details of glaucoma and diabetic retinopathy. The authors begin with the cornea and lens, which project an image on the light-sensitive elements inside the eye, the photoreceptors, and how that process can be compromised by such disorders as cataracts and corneal disease. They go on to describe, among other things, how the photoreceptors capture light; retinal and visual cortical anatomy and physiology; and higher level visual processing that leads to perception. Cortical disorders such as amblyopia are discussed as well as specific deficits such as the inability to recognize faces, colors, or moving objects. Finally, they survey the evolution of our knowledge of vision, and speculate about future advances.