Three-dimensional Electron Microscopy of Macromolecular Assemblies - Hardcover

Three-Dimensional Electronic Microscopy of Macromolecular Assemblies is the first systematic introduction to single particle methods for reconstruction. It covers correlation alignment, classification, 3-D reconstruction, restoration, and interpretation of the resulting 3-D images oif macromolecular assemblies. It will be an indispensable resource for newcomers to the field and for all using or adopting these methods. Features: * Presents methods that offer an alternative to crystallographic techniques for molecules that cannot be crystallized * Describes methods that have been instrumental in exploring the three-dimensional structure of the nuclear pore complex, the calcium release channel,the ribosome, Chaperonins.